Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

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ea0035p27 | Adrenal cortex | ECE2014

A three generation family with low cortisol, CBG deficiency, chronic fatigue and pain, lipomatosis and behavioral alterations

Moia Stefania , Walker Gillian Elisabeth , Roccio Marta , Ricotti Roberta , Giglione Enza , Bellone Simonetta , Fanelli Flaminia , Bona Gianni , Prodam Flavia

Introduction: CBG is the main transport protein for glucocorticoids in blood. CBG gene is a member of the serine protease inhibitor family, located at chromosome 14q32. Inherited CBG deficiency (MIM 611489) is a rarely recessive disorder, and the phenotype associated includes low cortisol levels, presence of normal ACTH levels, hypotension and fatigue, although the exact pathophysiological mechanisms involved remain uncertain. We identified a family with a complex phe...
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ea0035p145 | Calcium and Vitamin D metabolism | ECE2014

The association between vitamin D deficiency and metabolic parameters in pediatric obesity is influenced by what surrogate index of sunlight exposure is used

Prodam Flavia , Zanetta Sara , Bellone Simonetta , Ricotti Roberta , Giglione Enza , Marolda Agostina , Petri Antonella , Zavattaro Marco , Aimaretti Gianluca , Bona Gianni

Introduction: The association between vitamin D (25(OH)D) levels and metabolic parameters is not confirmed in some population studies. 25(OH)D concentration in blood is influenced by seasons and this covariate may explain some discordant results. The first aim of our study was to evaluate the prevalence of 25(OH)D deficiency in a population of obesity children (2–18 years) living in the North of Italy (latitude, 45°27′n) with respect to the season. The...
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ea0081rc1.2 | Rapid Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2022

Glucose alterations, insulin resistance, hypertension, and activation of the renin-aldosterone system are strictly associated in pediatric obesity

Antoniotti Valentina , Amore Martina , Bellone Simonetta , Ricotti Roberta , De Grandi Roberta , Caputo Marina , Spadaccini Daniele , Mancioppi Valentina , Aimaretti Gianluca , Prodam Flavia

Background: The increase of global childhood obesity has led to an increase of associated co-morbidities also at a young age. The pro-inflammatory state and insulin resistance are two master regulators of several complications, including hypertension and pre-diabetes frequently connected in a complex cross-talk.Aim: To evaluate the relationship between glucose alterations and blood pressure and the pathogenetic involvement of the renin-aldosterone system...
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ea0081p602 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Mediterranean Diet and 12 months weight loss result in complex serum metabolomic and fecal metaproteomic changes in paediatric obesity

Spadaccini Daniele , Vita Vanella Virginia , Barberis Elettra , Ricotti Roberta , Bellone Simonetta , Bona Elisa , Antoniotti Valentina , Caputo Marina , Mancioppi Valentina , Rabbone Ivana , Manfredi Marcello , Prodam Flavia

Background: The relationship between composition and function of microbiota, obesity and nutrition has been increasingly studied and is still a challenge.Aims: To test whether in a group of 12 pediatric patients with obesity the treatment with a structured hospital and in-home Mediterranean Diet intervention had an impact on gut microbiota composition, function, and metabolite production, including Short chain fatty acids (SCFAs).M...
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ea0070aep373 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

The educational training to the Mediterranean diet-like pattern is followed by improvement in cardiometabolic parameters and ecology of the microbiome in children with obesity: Preliminary results of the GOOD DAY trial

Ricotti Roberta , Archero Francesca , Landoni Valentina , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Solito Arianna , Novello Giorgia , Gamalero Elisa , Mignone Flavio , Cavaletto Maria , Agosti Emanuela , Bona Elisa , Prodam Flavia

Introduction: In the pediatric population the progression of obesity-related diseases can be delayed or prevented through changes in lifestyle, including the promotion of a Mediterranean-like dietary (MD) pattern.Objective: We aimed to assess the efficacy of an educational training to MD based on gamification with respect to a conventional weight-loss treatment in obese pediatric subjects on weight decreased and cardiometabolic risk factors (GOOD-DAY Tri...
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ea0070oc3.5 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Supplementation with Bifidobacterium breve BR03 and Bifidobacterium breve B632 favoured weight loss and improved insulin metabolism in children and adolescents with obesity in the BIFI-OBESE cross-over, randomized placebo-controlled trial

Solito Arianna , Hasballa Iderina , Calgaro Matteo , Bozzi Cionci Nicole , Ricotti Roberta , Caputo Marina , Genoni Giulia , Monzani Alice , Archero Francesca , Bellone Simonetta , Bona Gianni , Agosti Emanuela , Aimaretti Gianluca , Amoruso Angela , Pane Marco , Vitulo Nicola , Di Gioia Diana , Prodam Flavia

Background: Variations in gut microbiota might impact metabolic functions like caloric intake and energy expenditure leading to body weight excess. Microbiota modulation may be a potential approach for obesity management, especially in subject characterized by specific microbial enterotypes.Objective: We aimed to assess the impact of probiotic treatment in obese children and adolescents, under diet control, on weight loss, glucose, and insulin homeostasi...
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ea0073aep166 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The ecology of the microbiome in children with obesity is associated to insulin resistance anddiet composition

Ricotti Roberta , Archero Francesca , Landoni Valentina , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Solito Arianna , Antoniotti Valentina , Gamalero Elisa , Massa Nadia , Mignone Flavio , Cavaletto Maria , Agosti Emanuela , Bona Elisa , Prodam Flavia

IntroductionIn the pediatric population, the progression of obesity-related diseases can be delayed or prevented through lifestyle changes, including the promotion of a Mediterranean-like dietary (MD) pattern.ObjectiveWe aimed to evaluate the gut microbiome ecology in relation to dietary and clinical parameters in the pediatric subjects with obesity recruited at baseline in a protocol on an educational traini...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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